In-silico reverse docking and in-vitro studies identified curcumin, 18α-glycyrrhetinic acid, rosmarinic acid, and quercetin as inhibitors of α-glucosidase and pancreatic α-amylase and lipid accumulation in HepG2 cells, important type 2 diabetes targets | Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds | Alps Pharmaceutical Ind. Co.,Ltd.

Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

In-silico reverse docking and in-vitro studies identified curcumin, 18α-glycyrrhetinic acid, rosmarinic acid, and quercetin as inhibitors of α-glucosidase and pancreatic α-amylase and lipid accumulation in HepG2 cells, important type 2 diabetes targets

Authors:: Kadima Samuel Tshiyoyo; Megan Jean Bester; June C. Serem; Zeno Apostolides

Reference:: Journal of Molecular StructureJournal of Molecular Structure; 2022; 1266; 133492

DOI:: 10.1016/j.molstruc.2022.133492

See Abstract

Key Words:: Quercetin; curcumin; 18α-glycyrrhetinic acid; rosmarinic acid; diabetes mellitus; α-amylase; α-glucosidase; molecular docking; HepG2; lipid accumulation

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