Human rotator cuff tears demonstrate an age-dependent increase in markers of cellular senescence and selective removal of senescent cells with dasatinib+quercetin increases genetic expression of COL1A1 in vitro | Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds | Alps Pharmaceutical Ind. Co.,Ltd.

Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

Human rotator cuff tears demonstrate an age-dependent increase in markers of cellular senescence and selective removal of senescent cells with dasatinib+quercetin increases genetic expression of COL1A1 in vitro

Authors:: Benjamin C. Hawthorne; Ian J. Wellington; Joshua T. Sabitsky; Kyle V. Murphy; Owen P. Karsmarski; Rohin O. Thomas; Matthew R. LeVasseur; Michael R. Mancini; Maxwell T. Trudeau; Sagar Gulati; Mary Beth R. McCarthy; Mark P. Cote; Ming Xu; Augustus D. Mazzocca

Reference:: Arthroscopy: The Journal of Arthroscopic & Related Surgery; 2024; 40; 34-44

DOI:: 10.1016/j.arthro.2023.05.036

See Abstract

Key Words:: Rotator cuff tissue; ex vivo; senescent cell markers; senescence-associated secretory phenotype; dasatinib; quercetin; senolytics; COL1A1

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