Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation | Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds | Alps Pharmaceutical Ind. Co.,Ltd.

Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation

Authors:: Yue Ma; Panpan Xu; Hengrui Xing; Yue Zhang; Tingting Li; Xueman Ding; Li Liu; Qiang Niu

Reference:: Ecotoxicology and Environmental Safety; 2024; 274; 116195

DOI:: 10.1016/j.ecoenv.2024.116195

See Abstract

Key Words:: Sodium fluoride; rats; GSDME/HMGB1 axis; lysosomal membrane permeabilization; reactive oxygen species; renal protection; animal experiments

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