Rutin Outperforms Gallic Acid in Mitigating Carbon Tetrachloride-Induced Nephrotoxicity: Integrated In Silico (Docking, MD Simulations, DFT) and In Vivo Mechanistic Validation | Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds | Alps Pharmaceutical Ind. Co.,Ltd.

Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

Rutin Outperforms Gallic Acid in Mitigating Carbon Tetrachloride-Induced Nephrotoxicity: Integrated In Silico (Docking, MD Simulations, DFT) and In Vivo Mechanistic Validation

Authors:: Hend A. Essa; Abdallah Ashraf; Mohamed Elsheikh

Reference:: Toxicology Reports; 2026; 16; 102214

DOI:: 10.1016/j.toxrep.2026.102214

See Abstract

Key Words:: Carbon tetrachloride; rats; rutin; gallic acid; renal protection; animal experiments; molecular docking; TNF-α converting enzyme; IL-6 receptor α; molecular dynamics simulation

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