Low concentration of rutin treatment might alleviate the cardiotoxicity effect of pirarubicin on cardiomyocytes via activation of PI3K/AKT/mTOR signaling pathway
- Reference:
- Bioscience Reports
- 2019
- 39
- BSR20190546
- DOI:
- 10.1042/BSR20190546
Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds
Here we provide a literature database for flavonoids, focused upon quercetin, rutin, isorhamnetin, and their related compounds. Original papers and reviews about in vitro, in vivo, and clinical pharmacologies are contained here.
Search
- Result:
- 21-30 Hits of 34
Quercetin inhibits the NOX2/ROS-mediated NF-κB/TXNIP signaling pathway to ameliorate pyroptosis of cardiomyocytes to relieve sepsis-induced cardiomyopathy
- Reference:
- Toxicology and Applied Pharmacology
- 2023
- 477
- 116672
- DOI:
- 10.1016/j.taap.2023.116672
Peroxisome proliferator-activated receptor γ (PPARγ) mediates the protective effect of quercetin against myocardial ischemia-reperfusion injury via suppressing the NF-κB pathway
- Reference:
- American Journal of Translational Research
- 2016
- 8
- 5169–5186
- DOI:
- ?
Quercetin attenuates myocardial ischemia-reperfusion injury via downregulation of the HMGB1-TLR4-NF-κB signaling pathway
- Reference:
- American Journal of Translational Research
- 2018
- 10
- 1273–1283
- DOI:
- ?
Quercetin attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways
- Reference:
- Gene
- 2016
- 577
- 275-280
- DOI:
- 10.1016/j.gene.2015.12.012
Quercetin and Its Derivative Counteract Palmitate-Dependent Lipotoxicity by Inhibiting Oxidative Stress and Inflammation in Cardiomyocytes
- Authors:
- Maria Concetta Granieri
- Carmine Rocca
- Anna De Bartolo
- Immacolata Cristina Nettore
- Vittoria Rago
- Naomi Romeo
- Jessica Ceramella
- Annaluisa Mariconda
- Paolo Emidio Macchia
- Paola Ungaro
- Maria Stefania Sinicropi
- Tommaso Angelone
- Reference:
- International Journal of Environmental Research and Public Health
- 2023
- 20
- 3492
- DOI:
- 10.3390/ijerph20043492
Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro
- Authors:
- Jing Sun
- Guibo Sun
- Xiangbao Meng
- Hongwei Wang
- Yun Luo
- Meng Qin
- Bo Ma
- Min Wang
- Dayong Cai
- Peng Guo
- Xiaobo Sun
- Reference:
- PLoS ONE
- 2013
- 8
- e64526
- DOI:
- 10.1371/journal.pone.0064526
Rutin bioconjugates as potential nutraceutical prodrugs: An in vitro and in ovo toxicological screening
- Authors:
- Cristina Adriana Dehelean
- Dorina Coricovac
- Iulia Pinzaru
- Iasmina Marcovici
- Ioana Gabriela Macasoi
- Alexandra Semenescu
- Geza Lazar
- Simona Cinta Pinzaru
- Isidora Radulov
- Ersilia Alexa
- Octavian Cretu
- Reference:
- Frontiers in Pharmacology
- 2022
- 13
- 1000608
- DOI:
- 10.3389/fphar.2022.1000608
Formulation and Optimization of Quercetin Nanoemulsion for Enhancing Its Dissolution Rate, Bioavailability and Cardioprotective Activity
- Authors:
- Nimer Alsabeelah
- Vinay Kumar
- Reference:
- Journal of Cluster Science
- 2023
- 34
- 1893–1906
- DOI:
- 10.1007/s10876-022-02351-1
Quercetin Mitigates Cisplatin-Induced Oxidative Damage and Apoptosis in Cardiomyocytes through Nrf2/HO-1 Signaling Pathway
- Authors:
- Shih-Hao Wang
- Kun-Ling Tsai
- Wan-Ching Chou
- Hui-Ching Cheng
- Yu-Ting Huang
- Hsiu-Chung Ou
- Yun-Ching Chang
- Reference:
- The American Journal of Chinese Medicine
- 2022
- 50
- 1281-1298
- DOI:
- 10.1142/S0192415X22500537