Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

Here we provide a literature database for flavonoids, focused upon quercetin, rutin, isorhamnetin, and their related compounds. Original papers and reviews about in vitro, in vivo, and clinical pharmacologies are contained here.

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Result:: 21-30 Hits of 39

Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice

Authors:: Andrés Pastor-Fernández; Antonio R. Bertos; Arantzazu Sierra-Ramírez; Javier del Moral-Salmoral; Javier Merino; Ana I. de Ávila; Cristina Olagüe; Ricardo Villares; Gloria González-Aseguinolaza; María Ángeles Rodríguez; Manuel Fresno; Nuria Gironés; Matilde Bustos; Cristian Smerdou; Pablo Jose Fernandez-Marcos; Cayetano von Kobbe

Reference:: Aging Cell; 2023; 22; e13771

DOI:: 10.1111/acel.13771

See Abstract

Repurpose dasatinib and quercetin: Targeting senescent cells ameliorates postmenopausal osteoporosis and rejuvenates bone regeneration

Authors:: Ying Wang; Lingbin Che; Xi Chen; Zirui He; Dianwen Song; Yuan Yuan; Changsheng Liu

Reference:: Bioactive Materials; 2023; 25; 13-28

DOI:: 10.1016/j.bioactmat.2023.01.009

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Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age

Authors:: Torikul Islam; Eric Tuday; Shanena Allen; John Kim; Daniel W. Trott; William L. Holland; Anthony J. Donato; Lisa A. Lesniewski

Reference:: Aging Cell; 2023; 22; e13767

DOI:: 10.1111/acel.13767

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Reduction in Lens Epithelial Cell Senescence Burden through Dasatinib Plus Quercetin or Rapamycin Alleviates D-Galactose-Induced Cataract Progression

Authors:: Yinhao Wang; Yulin Tseng; Keyu Chen; Xinglin Wang; Zebin Mao; Xuemin Li

Reference:: Journal of Functional Biomaterials; 2023; 14; 6

DOI:: 10.3390/jfb14010006

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Combined use of dasatinib and quercetin alleviates overtraining-induced deficits in learning and memory through eliminating senescent cells and reducing apoptotic cells in rat hippocampus

Authors:: Chenkang Wang; Yu Kang; Panwen Liu; Weiwei Liu; Wenhui Chen; Toshihiko Hayashi; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Takashi Ikejima

Reference:: Behavioural Brain Research; 2023; 440; 114260

DOI:: 10.1016/j.bbr.2022.114260

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A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age-related and kidney diseases

Authors:: Khalid Saad Alharbi; Obaid Afzal; Abdulmalik Saleh Alfawaz Altamimi; Waleed Hassan Almalki; Imran Kazmi; Fahad A. Al-Abbasi; Sami I. Alzarea; Hafiz A. Makeen; Mohammed Albratty

Reference:: Journal of Food Biochemistry; 2022; 46; e14471

DOI:: 10.1111/jfbc.14471

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Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice

Authors:: Edward Fielder; Tengfei Wan; Ghazaleh Alimohammadiha; Abbas Ishaq; Evon Low; B. Melanie Weigand; George Kelly; Craig Parker; Brigid Griffin; Diana Jurk; Viktor I. Korolchuk; Thomas von Zglinicki; Satomi Miwa

Reference:: eLife; 2022; 11; e75492

DOI:: 10.7554/eLife.75492

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The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Reference:: Aging Cell; 2015; 14; 644-658

DOI:: 10.1111/acel.12344

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Senolytic Therapy to Modulate the Progression of Alzheimer’s Disease (SToMP-AD): A Pilot Clinical Trial

Authors:: Mitzi M. Gonzales; V. R. Garbarino; E. Marques Zilli; R. C. Petersen; J. L. Kirkland; T. Tchkonia; N. Musi; S. Seshadri; S. Craft; Miranda E. Orr

Reference:: The Journal of Prevention of Alzheimer’s Disease; 2022; 9; 22–29

DOI:: 10.14283/jpad.2021.62

See Abstract

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

Authors:: LaTonya J. Hickson; Larissa G.P. Langhi Prata; Shane A. Bobart; Tamara K. Evans; Nino Giorgadze; Shahrukh K. Hashmi; Sandra M. Herrmann; Michael D. Jensen; Qingyi Jia; Kyra L. Jordan; Todd A. Kellogg; Sundeep Khosla; Daniel M. Koerber; Anthony B. Lagnado; Donna K. Lawson; Nathan K. LeBrasseur; Lilach O. Lerman; Kathleen M. McDonald; James L. Kirkland

Reference:: eBioMedicine; 2019; 47; 446-456

DOI:: 10.1016/j.ebiom.2019.08.069

See Abstract