Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

Here we provide a literature database for flavonoids, focused upon quercetin, rutin, isorhamnetin, and their related compounds. Original papers and reviews about in vitro, in vivo, and clinical pharmacologies are contained here.

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Result:: 31-40 Hits of 260

Quercetin influences intestinal dysbacteriosis and delays alveolar epithelial cell senescence by regulating PTEN/PI3K/AKT signaling in pulmonary fibrosis

Authors:: Wenjuan Wu; Xinhui Wu; Lingxiao Qiu; Ruijie Wan; Xiaoming Zhu; Song Chen; Xinying Yang; Xueya Liu; Jizhen Wu

Reference:: Naunyn-Schmiedeberg's Archives of Pharmacology; 2024; 397; 4809–4822

DOI:: 10.1007/s00210-023-02913-8

See Abstract

Alleviatory effect of isoquercetin on benign prostatic hyperplasia via IGF-1/PI3K/Akt/mTOR pathway

Authors:: Young-Jin Choi; Meiqi Fan; Nishala Erandi Wedamulla; Yujiao Tang; Eun-Kyung Kim

Reference:: Food Science and Human Wellness; 2024; 13; 1698-1710

DOI:: 10.26599/FSHW.2022.9250216

See Abstract

Effect of rutin on spinal cord injury through inhibition of the expression of MIP-2 and activation of MMP-9, and downregulation of Akt phosphorylation

Authors:: Peng Zhang; Xun Ma

Reference:: Molecular Medicine Reports; 2015; 12; 7554-7560

DOI:: 10.3892/mmr.2015.4357

See Abstract

Quercetin-3-O-β-d-glucuronide in the Nuciferine Leaf Polyphenol Extract Promotes Neurogenesis Involving the Upregulation of the Tropomyosin Receptor Kinase (Trk) Receptor and AKT/Phosphoinositide 3-Kinase Signaling Pathway

Authors:: Yi-Ju Lee; Sin-Rong Chen; Ping-En Ko; Mon-Yuan Yang; Meng-Hsuin Yu; Chau-Jong Wang; Huei-Jane Lee

Reference:: Journal of Agricultural and Food Chemistry; 2023; 71; 15582–15592

DOI:: 10.1021/acs.jafc.3c03894

See Abstract

Quercetin postconditioning attenuates myocardial ischemia/reperfusion injury in rats through the PI3K/Akt pathway

Authors:: Y. Wang; Z. Z. Zhang; Y. Wu; J. J. Ke; X. H. He; Y. L. Wang

Reference:: Brazilian Journal of Medical and Biological Research; 2013; 46; 861-867

DOI:: 10.1590/1414-431X20133036

See Abstract

Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling pathway

Authors:: Lin Li; Weifeng Jiang; Baojian Yu; Huiqi Liang; Shihui Mao; Xiaowei Hu; Yan Feng; Jiadong Xu; Lisheng Chu

Reference:: Biomedicine & Pharmacotherapy; 2023; 168; 115653

DOI:: 10.1016/j.biopha.2023.115653

See Abstract

Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway

Authors:: Gan Li; Yiwei Ren; Enmeng Li; Kai Deng; Chao Qu; Junxiang Zhang; Li Zhang; Xingjie Wang; Jie Lian; Huayou Zhou; Zijun Wang; Tianli Shen; Xuqi Li; Zhengdong Jiang

Reference:: Journal of Ethnopharmacology; 2024; 319; 117242

DOI:: 10.1016/j.jep.2023.117242

See Abstract

Quercetin-targeted AKT1 regulates the Raf/MEK/ERK signaling pathway to protect against doxorubicin-induced nephropathy in mice

Authors:: Wang Yufang; Liu Mingfang; Huang Nan; Wang Tingting

Reference:: Tissue and Cell; 2023; 85; 102229

DOI:: 10.1016/j.tice.2023.102229

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Isorhamnetin Exerts Antifibrotic Effects by Attenuating Platelet-Derived Growth Factor-BB-induced HSC-T6 Cells Activation via Suppressing PI3K-AKT Signaling Pathway

Authors:: Mojtaba Rashidi; Emad Matour; Hasti Beheshti Nasab; Maryam Cheraghzadeh; Elham Shakerian

Reference:: Iranian Biomedical Journal; 2023; 27; 199–204

DOI:: 10.52547/ibj.3948

See Abstract

Low concentration of rutin treatment might alleviate the cardiotoxicity effect of pirarubicin on cardiomyocytes via activation of PI3K/AKT/mTOR signaling pathway

Authors:: Junjie Fei; Yi Sun; Yuyin Duan; Jianming Xia; Songhua Yu; Peigang Ouyang; Teng Wang; Guimin Zhang

Reference:: Bioscience Reports; 2019; 39; BSR20190546

DOI:: 10.1042/BSR20190546

See Abstract