Senolytics Cocktail Dasatinib and Quercetin Alleviate Human Umbilical Vein Endothelial Cell Senescence via the TRAF6-MAPK-NF-κB Axis in a YTHDF2-Dependent Manner
- Reference:
- Gerontology
- 2022
- 68
- 920–934
- DOI:
- 10.1159/000522656
Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds
Here we provide a literature database for flavonoids, focused upon quercetin, rutin, isorhamnetin, and their related compounds. Original papers and reviews about in vitro, in vivo, and clinical pharmacologies are contained here.
Search
- Result:
- 31-39 Hits of 39
Dasatinib plus quercetin attenuates some frailty characteristics in SAMP10 mice
- Authors:
- Hidetaka Ota
- Ayuto Kodama
- Reference:
- Scientific Reports
- 2022
- 12
- 2425
- DOI:
- 10.1038/s41598-022-06448-5
Deletion of SA β-Gal+ cells using senolytics improves muscle regeneration in old mice
- Authors:
- Cory M. Dungan
- Kevin A. Murach
- Christopher J. Zdunek
- Zuo Jian Tang
- Georgia L. VonLehmden
- Camille R. Brightwell
- Zachary Hettinger
- Davis A. Englund
- Zheng Liu
- Christopher S. Fry
- Antonio Filareto
- Michael Franti
- Charlotte A. Peterson
- Reference:
- Aging Cell
- 2022
- 21
- e13528
- DOI:
- 10.1111/acel.13528
Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice
- Authors:
- Tatiana Dandolini Saccon
- Ravinder Nagpal
- Hariom Yadav
- Marcelo Borges Cavalcante
- Allancer Divino de Carvalho Nunes
- Augusto Schneider
- Adam Gesing
- Brian Hughes
- Matthew Yousefzadeh
- Tamar Tchkonia
- James L. Kirkland
- Laura J. Niedernhofer
- Paul D. Robbins
- Michal M. Masternak
- Reference:
- The Journals of Gerontology: Series A
- 2021
- 76
- 1895–1905
- DOI:
- 10.1093/gerona/glab002
Senolytic Cocktail Dasatinib Plus Quercetin Enhances the Antitumor Effect of Senescence-Inducing Radiotherapy in a Preclinical Model of Melanoma
- Reference:
- International Journal of Radiation Oncology - Biology - Physics
- 2021
- 111
- S57
- DOI:
- 10.1016/j.ijrobp.2021.07.146
Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin
- Authors:
- Marco Raffaele
- Kristina Kovacovicova
- Jan Frohlich
- Oriana Lo Re
- Sebastiano Giallongo
- Jude A. Oben
- Martin Faldyna
- Lenka Leva
- Antonino Giulio Giannone
- Daniela Cabibi
- Manlio Vinciguerra
- Reference:
- Cell Communication and Signaling
- 2021
- 19
- 44
- DOI:
- 10.1186/s12964-021-00731-0
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice
- Authors:
- Emanuel J. Novais
- Victoria A. Tran
- Shira N. Johnston
- Kayla R. Darris
- Alex J. Roupas
- Garrett A. Sessions
- Irving M. Shapiro
- Brian O. Diekman
- Makarand V. Risbud
- Reference:
- Nature Communications
- 2021
- 12
- 5213
- DOI:
- 10.1038/s41467-021-25453-2
Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin
- Authors:
- Arantzazu Sierra-Ramirez
- José Luis López-Aceituno
- Luis Filipe Costa-Machado
- Adrián Plaza
- Marta Barradas
- Pablo Jose Fernandez-Marcos
- Reference:
- Aging
- 2020
- 12
- 11337—11348
- DOI:
- 10.18632/aging.103607
Senolytic Drugs, Dasatinib and Quercetin, Attenuate Adipose Tissue T Lymphocyte Infiltration and Improve Metabolic Function in Old Mice
- Reference:
- The FASEB Journal
- 2021
- 35, Special Issue:Experimental Biology 2021 Meeting Abstracts, Physiology
- 10.1096/fasebj.2021.35.S1.01969
- DOI:
- 10.1096/fasebj.2021.35.S1.01969