A study based on reverse network pharmacology of kidney stones identified that quercetin targets the myosin light chain kinase/myosin light chain 2 pathway in human kidney HK-2 cells | Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds | Alps Pharmaceutical Ind. Co.,Ltd.

Literature Database for Quercetin, Rutin, Isorhamnetin, and Their Related Compounds

A study based on reverse network pharmacology of kidney stones identified that quercetin targets the myosin light chain kinase/myosin light chain 2 pathway in human kidney HK-2 cells

Authors:: Haozhen Wang; Ziyin Lu; Wenyu Yang; Xiang Li; Mingdong Gao; Chaojie Duan; Yang Li; Xiuli Lu; Bing Gao

Reference:: Asian Journal of Urology; 2025; 12; in press

DOI:: 10.1016/j.ajur.2025.01.007

See Abstract

Key Words:: Nephrolithiasis; reverse network pharmacology; quercetin; MLCK/MLC2; renal tubular proximal epithelial cells; HK-2; molecular docking; molecular dynamics simulation

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